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Developing safer blood pressure medicines

Developing safer and more effective blood pressure lowering drugs may be possible due to a new study published in the Journal of Pharmacology and Experimental Therapeutics.

The results may help researchers predict whether drugs intended for other conditions, such as Alzheimer’s disease and epilepsy, affect blood pressure levels.

The drug research

Many people use blood pressure lowering medications, but may experience side effects from the drugs. On the other hand, those taking medicines for other conditions may find it affects their blood pressure adversely.

Researchers investigated potassium channels and found that when a drug blocks these potassium channels blood pressure increases. Conversely, if a drug opens up potassium channels, blood pressure goes down.

For example, an epilepsy drug may lower blood pressure because it opens the potassium channel. However, an Alzheimer’s disease drug, which blocks the potassium channel, may have the opposite effect of increasing blood pressure.

Researchers conclusions

“By observing the impact of a drug on these particular potassium channels, you can predict its impact on blood pressure.” researcher Kenneth Byron said. “We still are in the early stages of this work, but with continued funding, we believe our findings could lead to major benefits in the treatment of hypertension or stroke.”


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Kellie is 37 years old and together with her brother Steve makes up the My Health Software team.

She helps on the websites and gathering news for the programs. Kellie worked in the medical industry prior to having her two children (8 and 6) and has a strong interest in self awareness and management of health conditions.


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