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The ‘polypill’ cuts heart risks

I have reviewed studies on ‘combination pills’ before, but never a ‘polypill’ with 5 drugs in 1 pill!

The study results are very promising. Taking the polypill was shown to be easy, cheap and effective in cutting heart risk.

What’s in the ‘polypill’?

The 5 in 1 polypill contained 3 blood pressure lowering medications, a statin and aspirin. Specifically it contained:

  • The beta-blocker atenolol – to lower blood pressure.
  • The ACE inhibitor ramipril – to lower blood pressure.
  • The diuretic hydrocholorothiazide – to lower blood pressure.
  • The statin simvastatin – to lower cholesterol.
  • 100 milligrams of aspirin – to reduce the risk of blood clot.

The ‘polypill’ study

Researchers at McMaster University in Hamilton, Ontario studied 2,053 healthy men and women. The participants took 1 ‘polypill’ a day for 3 months.

Compared to groups not receiving the pill, the polypill reduced systolic blood pressure by 7.4 points and diastolic blood pressure by 5.6 points. In addition, LDL or “bad” cholesterol was reduced by 25% in the polypill group. The decrease in heart rate and blood clotting in the polypill group was similar compared to those who took just a beta-blocker or aspirin alone.

The researchers felt that taking a single pill was easy for the participants to do, which helped to increase compliance throughout the study.

Another potential benefit reported by the researchers would be the lower cost by having less pills to take each day.

The study results were published in The Lancet.

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About Kellie

Kellie is 37 years old and together with her brother Steve makes up the My Health Software team.

She helps on the websites and gathering news for the programs. Kellie worked in the medical industry prior to having her two children (8 and 6) and has a strong interest in self awareness and management of health conditions.


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