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Single-pill drug combination effective

The international blood pressure study ACCOMPLISH has shown that single pill combination drugs are effective in controlling blood pressure for more than 75% of patients. The study also showed diuretic treatment, usually tried first by doctors to be less effective at reducing the rate of heart attack and stroke.

Drug combination study

The study involved 11,506 people who took a single tablet that included two medications.

Those in Group 1 had a 20% reduction in cardiovascular events such as; cardiovascular deaths, heart attacks and strokes.

Researchers comments

Kenneth Jamerson, the study leader from the University of Michigan, “This robust study showed us that switching patients to a single-pill combination meant that twice as many patients got to their blood pressure goal, regardless of previous therapy.”

He added, “The significant reduction in cardiovascular events we observed in patients will, I hope, show physicians that earlier use of a combination medication, especially with amlodipine, may be in the best interest of patients.”

The study funded by Novartis was so significant that the trial was stopped early.


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